SCHEMBL357884

SCHEMBL357884

CS(=O)(=O)OCCOCCOCCOCCOCCCCCCCCCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.45
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MMP9 P14780 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12390525 0.95 KIF11 (0.47) KIF11
SCHEMBL9999946 0.95 KIF11 (0.47) KIF11
SCHEMBL4804197 0.89 KIF11 (0.49) KIF11
SCHEMBL3727203 0.86 KIF11 (0.51) KIF11KDM4EUSP2ALDH1A1LMNA
SCHEMBL5057736 0.84 KIF11 (0.45) KIF11ALDH1A1
SCHEMBL4534936 0.84 KIF11 (0.45) KIF11ALDH1A1
SCHEMBL10744128 0.83 KIF11 (0.54) KIF11
SCHEMBL4534194 0.79 KIF11 (0.45) KIF11
SCHEMBL9889271 0.79 KIF11 (0.45) KIF11
SCHEMBL1345862 0.78 KIF11 (0.43) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023033519-A1 NANOMACHINERY FOR PREVENTION OR TREATMENT OF CANCER 울산과학기술원 2023-03-09 WO disclosed
US-20120015372-A1 METHODS AND COMPOSITIONS FOR PATHOGEN DETECTION USING FLUORESCENT POLYMER SENSORS UNIVERSITY OF MASSACHUSETTS (US) 2012-01-19 US disclosed
US-8021891-B2 Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-09-20 US disclosed
US-8021891-B2 Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-09-20 US disclosed
US-8003404-B2 Methods and compositions for pathogen detection using nanoparticle-fluorescent polymer complexes UNIVERSITY OF MASSACHUSETTS (US) 2011-08-23 US disclosed
US-20100021960-A1 Methods and compositions for pathogen detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-01-28 US disclosed
US-20090221099-A1 Methods and compositions for protein detection using fluorescent polymer sensors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-03 US disclosed