SCHEMBL9889936

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9889927	0.89	PDK2 (0.36)	PDK2ALOX15MAPTRAB9AHSD17B1
	SCHEMBL9889933	0.87	PDK2 (0.34)	PDK2ALOX15
	SCHEMBL12222874	0.87	PDK2 (0.35)	PDK2ALOX15MAPTNPC1ALDH1A1
	SCHEMBL1636523	0.82	PDK2 (0.31)	PDK2
	SCHEMBL1636519	0.82	PDK2 (0.31)	PDK2
	SCHEMBL9889925	0.80	PDK2 (0.36)	PDK2KDM4EHSD17B1HSD17B2ELANE
	SCHEMBL10274039	0.78	—	—
	SCHEMBL9889935	0.78	PDK2 (0.41)	PDK2HSD17B1HSD17B2
	SCHEMBL27612407	0.78	PDK2 (0.47)	PDK2MAPTNPC1RAB9ANPSR1
	SCHEMBL536401	0.76	MMP2 (0.46)	PDK2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.