SCHEMBL989003

SCHEMBL989003

Cc1nc(N(C)C)nc(CN(C)C(=O)O)c1C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.39
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 3/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 2/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
CREBBP Q92793 1/20 0.32
HTT P42858 2/20 0.32
TSHR P16473 1/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
GAA P10253 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9361439 0.75 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2KDM4ELMNAPOLB
SCHEMBL16796103 0.70 PDK1 (0.34)
SCHEMBL14297683 0.69 LMNA (0.59) HPGDALDH1A1SMN1; SMN2KDM4ELMNA
Altretamine SCHEMBL28503842 0.66 LMNA (0.65) HPGDALDH1A1SMN1; SMN2KDM4ELMNA
Altretamine SCHEMBL28892626 0.65 LMNA (0.61) HPGDALDH1A1SMN1; SMN2KDM4ELMNA
SCHEMBL27238455 0.63 ACACB (0.32) HPGDALDH1A1
SCHEMBL13647010 0.61 LMNA (0.48) HPGDLMNAPOLBHSD17B10CYP1A2
Pirimicarb SCHEMBL29407096 0.61 NPSR1 (0.46) HPGDALDH1A1SMN1; SMN2KDM4ELMNA
Pirimicarb SCHEMBL26523 0.61 NPSR1 (0.46) HPGDALDH1A1SMN1; SMN2KDM4ELMNA
Pirimicarb SCHEMBL1423368 0.60 NPSR1 (0.43) HPGDALDH1A1SMN1; SMN2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1722633-B1 Use of a insecticidal composition againt mosquitoes, namely for impregnation of mosquito nets INST RECH POUR LE DÉVELOPPEMENT IRD (FR) 2014-06-18 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
US-7793920-B2 barrier against insect; the net structure made of polymer fibers is impregnated with an insecticide; preventing the low flying insects from entering open-air area; black color; invisible to certain insects VESTERGAARD SA (CH) 2010-09-14 US claimed
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
US-20070122437-A1 Novel insecticide composition and use thereof particularly for impregnating mosquito nets, fly screens and the like INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2007-05-31 US claimed
EP-1722633-A2 NEW INSECTICIDE COMPOSITION AND ITS USE, NAMELY FOR IMPREGNATION OF MOSQUITO NETS Institut de Recherche pour le Développement ( IRD) (FR) 2006-11-22 EP claimed
EP-1697578-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-09-06 EP claimed
WO-2005079577-A2 NOVEL INSECTICIDE COMPOSITION AND USE THEREOF PARTICULARLY FOR IMPREGNATING MOSQUITO NETS, FLY SCREENS AND THE LIKE INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2005-09-01 WO claimed
WO-2005064072-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 WO claimed
US-20050132500-A1 Composition for impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2005-06-23 US claimed
EP-1411764-B1 A FENCING DISEASE CONTROL TEXTILES APS (DK) 2004-12-29 EP claimed
US-20040004210-A1 Fencing VESTERGAARD SA (CH) 2004-01-08 US claimed
EP-0944313-B1 INSECTICIDAL AND MITICIDAL COMPOSITIONS BASF AG (DE) 2002-09-25 EP claimed
WO-2001037662-A1 COMPOSITION FOR IMPREGNATION OF FABRICS AND NETTINGS DCT APS (DK) 2001-05-31 WO claimed
EP-0017738-B1 AN INSECTICIDAL AND MITICIDAL COMPOSITION WHICH CONTAINS A CARBAMATE AND AN ORGANIC PHOSPHORUS COMPOUND, AND A METHOD OF CONTROLLING INSECTS AND MITES THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-08 EP claimed
US-4315017-A Triazole derivatives BASF AKTIENGESELLSCHAFT (DE) 1982-02-09 US claimed
JP-11089568-A None JP disclosed
JP-56079608-A None JP disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests GAP43, GRN, DDT HPGD 3682/4885ALDH1A1 3986/4885SMN1; SMN2 3106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.