SCHEMBL9890313

SCHEMBL9890313

c1ccc2c(c1)c1ccccc1n2-c1ccc2oc3cc4oc5ccc(-n6c7ccccc7c7ccccc76)cc5c4cc3c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MAOA P21397 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
AHR P35869 3/20 0.41
KMT2A Q03164 3/20 0.41
NPC1 O15118 3/20 0.41
MEN1 O00255 2/20 0.41
RAB9A P51151 2/20 0.41
CHRNA7 P36544 1/20 0.36
KCNH2 Q12809 1/20 0.36
CYP1A2 P05177 2/20 0.35
GLA P06280 1/20 0.34
CYP3A4 P08684 1/20 0.34
PGAM1 P18669 1/20 0.34
CASP1 P29466 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890074 0.95 KDM4E (0.48) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL5028280 0.95 KDM4E (0.52) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL29551183 0.95 KDM4E (0.52) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL9890367 0.94 KDM4E (0.42) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL22249632 0.93 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL18381831 0.93 KDM4E (0.50) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL9890366 0.92 KDM4E (0.41) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL15867549 0.92 KDM4E (0.46) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL10144980 0.91 MAPT (0.50) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL14679586 0.91 KDM4E (0.48) KDM4EATML3MBTL1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10763440-B2 Organic electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2020-09-01 US disclosed
WO-2018116152-A1 SPECIFICALLY SUBSTITUTED LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2018-06-28 WO disclosed
US-20140306206-A1 Organic Electroluminescent Element, and Light Emitting Device, Display Device and Lighting Device Each Using Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2014-10-16 US disclosed
US-20140306206-A1 Organic Electroluminescent Element, and Light Emitting Device, Display Device and Lighting Device Each Using Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2014-10-16 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
EP-2301921-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2011-03-30 EP disclosed
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 KDM4E 990/4885ATM 3103/4885L3MBTL1 709/4885
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 KDM4E 990/4885ATM 3103/4885L3MBTL1 709/4885
US-10763440-B2 Organic electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element NR2E3, CRY2, CRY1 KDM4E 2843/4885ATM 4756/4885L3MBTL1 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.