Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MRE11 | P49959 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907810 | 0.92 | KCNQ1 (0.45) | KCNQ1TYRATMAIMP2LMNA | |
| SCHEMBL9890984 | 0.89 | MEN1 (0.35) | KCNQ1TYRMEN1KMT2AALDH1A1 | |
| SCHEMBL3429515 | 0.84 | TYR (0.45) | TYRATMLMNAMEN1KMT2A | |
| SCHEMBL9890981 | 0.82 | TYR (0.54) | TYRATMLMNAMEN1KMT2A | |
| SCHEMBL7906417 | 0.80 | KCNQ1 (0.37) | KCNQ1TYRLMNAMEN1KMT2A | |
| SCHEMBL13556405 | 0.79 | XIAP (0.48) | TYRATMLMNAMEN1KMT2A | |
| SCHEMBL9890978 | 0.79 | TYR (0.42) | TYRATMLMNAMEN1KMT2A | |
| SCHEMBL3429639 | 0.78 | TYR (0.46) | TYRATMLMNAMEN1KMT2A | |
| SCHEMBL10266218 | 0.78 | ALDH1A1 (0.48) | TYRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL22110048 | 0.76 | ALDH1A1 (0.47) | TYRLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | GYS2, CYP3A7, GBA1 | KCNQ1 425/4885TYR 1100/4885ATM 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.