Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034260 | 0.86 | TSHR (0.55) | TSHRCETPPKMNPSR1KCNH2 | |
| SCHEMBL389180 | 0.86 | TSHR (0.63) | TSHRCETPPKMFOLH1ALDH1A1 | |
| SCHEMBL19986359 | 0.77 | TSHR (0.53) | TSHRCETPPKMFOLH1ALDH1A1 | |
| SCHEMBL8619121 | 0.77 | TSHR (0.57) | TSHRCETPPKMFOLH1ALDH1A1 | |
| Ether SCHEMBL1680195 | 0.76 | TSHR (0.61) | TSHRCETPNPSR1FOLH1ALDH1A1 | |
| SCHEMBL12313535 | 0.75 | TSHR (0.55) | TSHRCETPPKMFOLH1ALDH1A1 | |
| SCHEMBL17537490 | 0.75 | TSHR (0.59) | TSHRCETPNPSR1FOLH1ALDH1A1 | |
| SCHEMBL5353833 | 0.74 | TSHR (0.61) | TSHRALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3367142 | 0.74 | TSHR (0.63) | TSHRCETPPKMFOLH1ALDH1A1 | |
| SCHEMBL26569501 | 0.74 | TSHR (0.53) | TSHRCETPPKMSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785629-B2 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | UNIVERSITE D'ORLEANS (FR) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | PNP, PHPT1, TYMP | TSHR 1146/4885CETP 3298/4885PKM 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.