Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 14/20 | 0.62 |
| ▸ | TK2 | O00142 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19196342 | 1.00 | TK1 (0.62) | TK1TK2MAPK1HPGD | |
| SCHEMBL19181903 | 0.83 | TK1 (0.63) | TK1TK2MAPK1 | |
| SCHEMBL6714052 | 0.82 | TK1 (0.57) | TK1TK2MAPK1HPGD | |
| SCHEMBL9891079 | 0.81 | GRIA1 (0.47) | TK1TK2 | |
| SCHEMBL9891078 | 0.81 | LMNA (0.51) | TK1TK2 | |
| SCHEMBL9891080 | 0.81 | ALDH1A1 (0.47) | TK1MAPK1 | |
| SCHEMBL9021896 | 0.81 | TK1 (0.56) | TK1TK2MAPK1HPGD | |
| SCHEMBL17478575 | 0.80 | TK1 (0.59) | TK1TK2MAPK1 | |
| SCHEMBL19182471 | 0.79 | TK1 (0.62) | TK1TK2 | |
| SCHEMBL19182467 | 0.79 | TK1 (0.62) | TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443130-B1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | CENTRE NAT RECH SCIENT (FR) | 2016-08-03 | — | — | EP | disclosed |
| US-8785629-B2 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-8785629-B2 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | UNIVERSITE D'ORLEANS (FR) | 2012-06-07 | — | — | US | disclosed |
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | UNIVERSITE D'ORLEANS (FR) | 2012-06-07 | — | — | US | disclosed |
| EP-2270021-A1 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | Centre National de la Recherche Scientifique (FR) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | PNP, PHPT1, TYMP | TK1 75/4885TK2 569/4885MAPK1 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.