Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891657 | 0.89 | EPHX1 (0.50) | ACHENFKB1MAPK1EPHX1BBOX1 | |
| SCHEMBL11382117 | 0.81 | KEAP1 (0.55) | KEAP1NFE2L2MAPK1EPHX1KMT2A | |
| SCHEMBL13466509 | 0.81 | KEAP1 (0.61) | KEAP1NFE2L2MAPK1EPHX1SMN1; SMN2 | |
| SCHEMBL14004334 | 0.81 | EPHX1 (0.48) | ACHEEPHX1KMT2AMEN1 | |
| SCHEMBL19171946 | 0.79 | EPHX1 (0.61) | KEAP1NFE2L2MAPK1EPHX1SMN1; SMN2 | |
| SCHEMBL9547610 | 0.79 | EPHX1 (0.61) | KEAP1NFE2L2MAPK1EPHX1SMN1; SMN2 | |
| SCHEMBL20443858 | 0.78 | ACHE (0.42) | ACHEBBOX1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8763339 | 0.77 | KDM4E (0.61) | ACHENFKB1CHRM2CHRM4CHRM5 | |
| SCHEMBL19171419 | 0.77 | EPHX1 (0.58) | KEAP1NFE2L2MAPK1EPHX1KMT2A | |
| SCHEMBL12558670 | 0.76 | EPHX1 (0.53) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120138473-A1 | ZINC PLATING BATH ADDITIVE AND ALKALINE NON-CYANIDE ZINC PLATING BATH | YUKEN INDUSTRY CO., LTD. (JP) | 2012-06-07 | — | — | US | disclosed |