Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893106 | 0.87 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPK14PKM | |
| SCHEMBL3824221 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2MAPK14CNR2 | |
| SCHEMBL13284530 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2MAPK14CNR2 | |
| SCHEMBL17833337 | 0.79 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2PKMEPHX2 | |
| SCHEMBL2402704 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2PKMMAPT | |
| SCHEMBL9891811 | 0.79 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2MAPK14CNR2 | |
| SCHEMBL13015655 | 0.77 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPK14CNR2 | |
| SCHEMBL26789822 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2MAPK14CNR2 | |
| SCHEMBL9892786 | 0.75 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2MAPK14CNR2 | |
| SCHEMBL11116702 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2MAPK14CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | ALDH1A1 3279/4885LMNA 4696/4885SMN1; SMN2 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.