SCHEMBL9893271

SCHEMBL9893271

CC(C)[C@@H](NC(=O)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)[C@@](C)(O)C1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9986625 1.00 CCR1 (0.70) CCR1
SCHEMBL9984607 1.00 CCR1 (0.70) CCR1
SCHEMBL1603622 0.91 CCR1 (0.84) CCR1
SCHEMBL3941399 0.89 CCR1 (0.74) CCR1
SCHEMBL2159622 0.89 CCR1 (0.74) CCR1
SCHEMBL9942108 0.86 CCR1 (0.63) CCR1
SCHEMBL9927489 0.86 CCR1 (0.63) CCR1
SCHEMBL10297056 0.83 CCR1 (0.81) CCR1
SCHEMBL9893233 0.83 CCR1 (0.71) CCR1
SCHEMBL9927490 0.83 CCR1 (0.71) CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582670-B1 PIPERIDINYL COMPOUND AS A MODULATOR OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL MYERS SQUIBB CO (US) 2015-12-16 EP disclosed
US-8642622-B2 Piperidinyl compound as a modulator of chemokine receptor activity BRISTOL-MYERS SQUIBB COMPANY (US) 2014-02-04 US disclosed
US-20120149733-A1 PIPERIDINYL COMPOUND AS A MODULATOR OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB COMPANY 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149733-A1 PIPERIDINYL COMPOUND AS A MODULATOR OF CHEMOKINE RECEPTOR ACTIVITY CCR2, CCR5, CCL11 CCR1 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.