Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14861418 | 0.82 | HPGD (0.42) | KDM4EALDH1A1HPGDPGRAR | |
| SCHEMBL14861467 | 0.82 | KEAP1 (0.45) | KEAP1L3MBTL1KMT2ATSHREP300 | |
| SCHEMBL3351205 | 0.82 | KDM4E (0.37) | L3MBTL1GAAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL3242695 | 0.82 | SMN1; SMN2 (0.43) | TSHRHSD17B10ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3521758 | 0.81 | KDM4E (0.34) | L3MBTL1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL17845939 | 0.79 | GLO1 (0.35) | TSHRHPGDSMN1; SMN2HTT | |
| SCHEMBL9893708 | 0.79 | TSHR (0.36) | TSHRGAAALDH1A1HTT | |
| SCHEMBL924510 | 0.78 | RXFP1 (0.40) | KMT2AGAAMEN1 | |
| SCHEMBL1533817 | 0.77 | TDP1 (0.37) | L3MBTL1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL415763 | 0.77 | KEAP1 (0.52) | KEAP1L3MBTL1KMT2ATSHREP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371337-B2 | β-lactamase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-21 | — | — | US | disclosed |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-11-05 | — | — | US | disclosed |
| US-9024071-B2 | Therapeutic compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140315861-A1 | BETA-LACTAMASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-10-23 | — | — | US | disclosed |
| WO-2013056163-A1 | BETA-LACTAMASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-18 | — | — | WO | disclosed |
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | KEAP1 1115/4885L3MBTL1 4393/4885KMT2A 4328/4885 |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | KEAP1 1115/4885L3MBTL1 4393/4885KMT2A 4328/4885 |
| US-20140315861-A1 | BETA-LACTAMASE INHIBITORS | BTD, GUSB, BLVRB | KEAP1 1340/4885L3MBTL1 62/4885KMT2A 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.