Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 4/20 | 0.47 |
| ▸ | ADCY3 | O60266 | 4/20 | 0.47 |
| ▸ | ADCY9 | O60503 | 4/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.47 |
| ▸ | ADCY8 | P40145 | 4/20 | 0.47 |
| ▸ | ADCY7 | P51828 | 4/20 | 0.47 |
| ▸ | ADCY2 | Q08462 | 4/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 4/20 | 0.47 |
| ▸ | ADCY4 | Q8NFM4 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9896499 | 0.90 | GCGR (0.47) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL9896229 | 0.85 | CSNK1D (0.50) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL9897046 | 0.84 | SCD (0.47) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL9895328 | 0.83 | CSNK1D (0.44) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL9896694 | 0.81 | GCGR (0.44) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL9894859 | 0.81 | RAB9A (0.46) | TP53LMNAGALK1SCDALDH1A1 | |
| SCHEMBL9896194 | 0.80 | CSNK1D (0.47) | TP53LMNAGALK1SCDHDAC6 | |
| SCHEMBL9895818 | 0.79 | PTPN1 (0.45) | TP53GALK1SCDSMN1; SMN2CTSS | |
| SCHEMBL9895023 | 0.79 | PTPN1 (0.45) | TP53GALK1SCDSMN1; SMN2CTSS | |
| SCHEMBL9894833 | 0.74 | PTPN1 (0.43) | TP53GALK1SCDSMN1; SMN2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | claimed |
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | P2RX7, P2RX3, P2RX2 | GCGR 224/4885ADCY6 660/4885ADCY3 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.