Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989812 | 1.00 | MAPT (0.50) | MAPTCACNA1BAPBA1TSHRTP53 | |
| SCHEMBL989814 | 1.00 | MAPT (0.50) | MAPTCACNA1BAPBA1TSHRTP53 | |
| Maleic Acid SCHEMBL27665820 | 0.86 | TSHR (0.56) | MAPTCACNA1BAPBA1TSHRTP53 | |
| SCHEMBL7675588 | 0.81 | MAPT (0.52) | MAPTCACNA1BAPBA1TSHRNPSR1 | |
| SCHEMBL9728289 | 0.81 | MAPT (0.52) | MAPTCACNA1BAPBA1TSHRNPSR1 | |
| SCHEMBL9728297 | 0.81 | MAPT (0.52) | MAPTCACNA1BAPBA1TSHRNPSR1 | |
| SCHEMBL10940750 | 0.80 | HTT (0.53) | TSHRTP53EGLN1EGLN3NPSR1 | |
| SCHEMBL10940759 | 0.80 | HTT (0.53) | TSHRTP53EGLN1EGLN3NPSR1 | |
| Fumaric Acid SCHEMBL11700020 | 0.77 | CRBN (0.70) | MAPTTSHRTP53EGLN1EGLN3 | |
| SCHEMBL9434744 | 0.75 | TSHR (0.43) | TSHRTP53EGLN1EGLN3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11400042-B2 | Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone | L'OREAL (FR) | 2022-08-02 | — | — | US | claimed |
| US-11298305-B2 | Compositions and methods for improving the appearance of the hair | L'OREAL (FR) | 2022-04-12 | — | — | US | claimed |
| EP-2988830-B1 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | OREAL (FR) | 2021-03-17 | — | — | EP | claimed |
| EP-2916808-B1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | OREAL (FR) | 2019-06-26 | — | — | EP | claimed |
| US-20190167552-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | L'OREAL (FR) | 2019-06-06 | — | — | US | claimed |
| US-20190117551-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER | L'OREAL (FR) | 2019-04-25 | — | — | US | claimed |
| US-20190021983-A1 | PROCESS FOR TREATING KERATIN FIBRES, COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING UREA OR A DERIVATIVE THEREOF, A POLYOL AND AN AMINO SILICONE | L'OREAL (FR) | 2019-01-24 | — | — | US | claimed |
| EP-3393435-A1 | PROCESS FOR TREATING KERATIN FIBRES, COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING UREA OR A DERIVATIVE THEREOF, A POLYOL AND AN AMINO SILICONE | L'Oréal (FR) | 2018-10-31 | — | — | EP | claimed |
| WO-2018000059-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | L'OREAL (FR) | 2018-01-04 | — | — | WO | claimed |
| CN-107200714-A | A kind of method for preparing orotic acid | 苏州长征－欣凯制药有限公司 | 2017-09-26 | — | — | CN | claimed |
| WO-1997049686-A1 | NOVEL POLYMERIZABLE ACYL IMIDAZOLIDINONE MONOMERS | CYTEC TECHNOLOGY CORP. (US) | 1997-12-31 | — | — | WO | claimed |
| WO-1997049687-A1 | POLYFUNCTIONAL CROSSLINKING ACYLIMIDAZOLIDINONE DERIVATIVES | CYTEC TECHNOLOGY CORP. (US) | 1997-12-31 | — | — | WO | claimed |
| US-5478919-A | Condensation polymerization of aspartic acid precursors and amino, hydroxy or carboxy-functional monomers to form polysuccinimide copolymer; hydrolysis to aspartic acid copolymer | DONLAR CORPORATION (US) | 1995-12-26 | — | — | US | claimed |
| EP-0080451-B1 | METHOD AND COMPOSITION FOR DIENE RUBBER TREATMENT | MONSANTO COMPANY (US) | 1985-09-18 | — | — | EP | claimed |
| EP-0079878-B1 | RUBBER COMPOSITIONS AND METHOD OF TREATING RUBBER | MONSANTO COMPANY (US) | 1985-07-10 | — | — | EP | claimed |
| US-4433114-A | SULFUR OR ORGANOSULFUR COMPOUNDS, MALEAMIC ACID OR DERIVATIVES, TACKINESS, GREEN STRENGTH | MONSANTO COMPANY (US) | 1984-02-21 | — | — | US | claimed |
| EP-0080451-A1 | Method and composition for diene rubber treatment | MONSANTO COMPANY (US) | 1983-06-01 | — | — | EP | claimed |
| EP-0079878-A1 | Rubber compositions and method of treating rubber | MONSANTO COMPANY (US) | 1983-05-25 | — | — | EP | claimed |
| US-4376189-A | Rubber compositions and method of treating rubber | MONSANTO COMPANY (US) | 1983-03-08 | — | — | US | claimed |
| US-4031064-A | MALEAMIC-FUMARAMIC ACID | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190021983-A1 | PROCESS FOR TREATING KERATIN FIBRES, COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING UREA OR A DERIVATIVE THEREOF, A POLYOL AND AN AMINO SILICONE | KRT18, CUTA, PUF60 | MAPT 112/4885CACNA1B 4718/4885APBA1 2744/4885 |
| US-20190167552-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | KRT18, OAT, CKMT1A; CKMT1B | MAPT 123/4885CACNA1B 3782/4885APBA1 3769/4885 |
| US-11298305-B2 | Compositions and methods for improving the appearance of the hair | KRT18, OAT, CKMT1A; CKMT1B | MAPT 123/4885CACNA1B 3782/4885APBA1 3769/4885 |
| US-20190117551-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER | KRT18, CUTA, MARK1 | MAPT 44/4885CACNA1B 4857/4885APBA1 1627/4885 |
| US-11400042-B2 | Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone | KRT18, CUTA, PUF60 | MAPT 112/4885CACNA1B 4718/4885APBA1 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.