SCHEMBL9898191

SCHEMBL9898191

CN(C)CCOC([SiH3])OCCN(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
CHRM2 P08172 4/20 0.43
CHRM1 P11229 4/20 0.43
CYP2D6 P10635 3/20 0.43
ADRA2A P08913 3/20 0.43
SLC6A2 P23975 3/20 0.43
SLC6A4 P31645 3/20 0.43
OPRM1 P35372 3/20 0.43
DRD3 P35462 3/20 0.43
SLC6A3 Q01959 3/20 0.43
CHRM4 P08173 3/20 0.43
CHRM5 P08912 3/20 0.43
CHRM3 P20309 3/20 0.43
ADRA2B P18089 2/20 0.43
HRH2 P25021 2/20 0.43
HTR2A P28223 2/20 0.43
HTR2C P28335 2/20 0.43
ADRA1A P35348 2/20 0.43
HRH1 P35367 2/20 0.43
HTR2B P41595 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444329 0.81
SCHEMBL7616550 0.77 CHRM2 (0.46) LMNACHRM2CHRM1CYP2D6ADRA2A
SCHEMBL10794918 0.77 CHRM2 (0.46) LMNACHRM2CHRM1CYP2D6ADRA2A
SCHEMBL27863698 0.75 CHRM2 (0.38) LMNACHRM2CHRM1CYP2D6ADRA2A
SCHEMBL5002708 0.74
SCHEMBL3973873 0.74 LMNA (0.45) LMNACHRM2CHRM1CYP2D6ADRA2A
SCHEMBL9898540 0.74 CHRM2 (0.41) LMNACHRM2CHRM1CYP2D6ADRA2A
SCHEMBL24578070 0.72
SCHEMBL18104599 0.72
SCHEMBL9897753 0.70 CHRM2 (0.38) LMNACHRM2CHRM1CYP2D6ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471798-B1 PROCESS FOR PRODUCTION OF SILANE COUPLING AGENTS BRIDGESTONE CORP (JP) 2015-08-19 EP claimed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
US-9150595-B2 Process for producing silane coupling agent BRIDGESTONE CORPORATION (JP) 2015-10-06 US disclosed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT HAO2, SAMM50, SKP2 LMNA 3112/4885CHRM2 4017/4885CHRM1 3830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.