SCHEMBL9897753

SCHEMBL9897753

CN(C)CCOC(CO[SiH3])OCCN(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.38
CHRM1 P11229 4/20 0.38
LMNA P02545 3/20 0.38
ADRA2A P08913 3/20 0.38
SLC6A2 P23975 3/20 0.38
SLC6A4 P31645 3/20 0.38
OPRM1 P35372 3/20 0.38
DRD3 P35462 3/20 0.38
SLC6A3 Q01959 3/20 0.38
CYP2D6 P10635 3/20 0.38
CHRM4 P08173 3/20 0.38
CHRM5 P08912 3/20 0.38
CHRM3 P20309 3/20 0.38
ADRA2B P18089 2/20 0.38
HRH2 P25021 2/20 0.38
HTR2A P28223 2/20 0.38
HTR2C P28335 2/20 0.38
ADRA1A P35348 2/20 0.38
HRH1 P35367 2/20 0.38
HTR2B P41595 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9897751 0.77 LMNA (0.35) CHRM2CHRM1LMNAADRA2ASLC6A2
SCHEMBL7566647 0.73 CHRM2 (0.42) CHRM2CHRM1LMNAADRA2ASLC6A2
SCHEMBL2124250 0.72
SCHEMBL9898540 0.71 CHRM2 (0.41) CHRM2CHRM1LMNAADRA2ASLC6A2
SCHEMBL9189154 0.71 CHRM2 (0.41) CHRM2CHRM1LMNAADRA2ASLC6A2
SCHEMBL38661194 0.71
SCHEMBL9898191 0.70 LMNA (0.43) CHRM2CHRM1LMNAADRA2ASLC6A2
SCHEMBL7557809 0.70 CHRM2 (0.39) CHRM2CHRM1LMNAADRA2ASLC6A2
SCHEMBL20135564 0.70 ADRB2 (0.35) TSHRCYP3A4CA1CA2
SCHEMBL7616550 0.69 CHRM2 (0.46) CHRM2CHRM1LMNAADRA2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471798-B1 PROCESS FOR PRODUCTION OF SILANE COUPLING AGENTS BRIDGESTONE CORP (JP) 2015-08-19 EP claimed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
US-9150595-B2 Process for producing silane coupling agent BRIDGESTONE CORPORATION (JP) 2015-10-06 US disclosed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT HAO2, SAMM50, SKP2 CHRM2 4017/4885CHRM1 3830/4885LMNA 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.