Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679081 | 0.93 | ALDH1A1 (0.33) | MEN1KMT2AMAPTL3MBTL1PDK2 | |
| SCHEMBL29539705 | 0.93 | ALDH1A1 (0.33) | MEN1KMT2AMAPTL3MBTL1PDK2 | |
| SCHEMBL29377775 | 0.88 | L3MBTL1 (0.46) | MEN1KMT2AMAPTL3MBTL1PDK2 | |
| SCHEMBL3721035 | 0.88 | L3MBTL1 (0.46) | MEN1KMT2AMAPTL3MBTL1PDK2 | |
| SCHEMBL10021911 | 0.87 | MAPT (0.32) | MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL2135089 | 0.86 | — | — | |
| SCHEMBL13957190 | 0.86 | — | — | |
| SCHEMBL6018281 | 0.86 | ALDH1A1 (0.36) | PDK2ALDH1A1 | |
| SCHEMBL2135063 | 0.86 | MEN1 (0.33) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL13228978 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708529-B2 | Bulk polymer composites | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-07-18 | — | — | US | disclosed |
| US-20150349262-A1 | Charge Transporting Semi-Conducting Material and Semi-Conducting Device | NOVALED GMBH (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20150349262-A1 | Charge Transporting Semi-Conducting Material and Semi-Conducting Device | NOVALED GMBH (DE) | 2015-12-03 | — | — | US | disclosed |
| US-9028728-B2 | Photochromic materials that include indeno-fused naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140346400-A1 | BULK POLYMER COMPOSITES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-27 | — | — | US | disclosed |
| WO-2013090610-A1 | BULK POLYMER COMPOSITES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2013086248-A1 | PHOTOCHROMIC MATERIALS THAT INCLUDE INDENO-FUSED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | TRANSITIONS OPTICAL INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | NQO1, INTS6, IPO4 | MEN1 4483/4885KMT2A 1529/4885MAPT 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.