SCHEMBL9898304

SCHEMBL9898304

CCCCCCCC(=O)SCCC[Si](OC)(OC)OCCN(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.34
LMNA P02545 1/20 0.33
DGKA P23743 1/20 0.33
ACHE P22303 2/20 0.32
PAOX Q6QHF9 1/20 0.31
ESR1 P03372 6/20 0.30
ESR2 Q92731 6/20 0.30
CES2 O00748 3/20 0.30
CES1 P23141 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899087 0.90 DNM1 (0.46) DNM1LMNADGKA
SCHEMBL9898055 0.86 DNM1 (0.36) DNM1DGKAACHEPAOXESR1
SCHEMBL30205650 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1
SCHEMBL30205788 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1
SCHEMBL30205659 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1
SCHEMBL96679 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1
SCHEMBL21049772 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1
SCHEMBL97747 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1
SCHEMBL21049771 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1
SCHEMBL30205784 0.84 LMNA (0.45) LMNADGKAESR1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471798-B1 PROCESS FOR PRODUCTION OF SILANE COUPLING AGENTS BRIDGESTONE CORP (JP) 2015-08-19 EP claimed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
US-9150595-B2 Process for producing silane coupling agent BRIDGESTONE CORPORATION (JP) 2015-10-06 US disclosed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT HAO2, SAMM50, SKP2 DNM1 1241/4885LMNA 3112/4885DGKA 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.