⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424522 | 0.72 | — | — | |
| SCHEMBL10629 | 0.70 | — | — | |
| SCHEMBL1446200 | 0.68 | — | — | |
| SCHEMBL42358 | 0.67 | — | — | |
| SCHEMBL554707 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL7538869 | 0.67 | — | — | |
| SCHEMBL597046 | 0.67 | NLRP3 (0.50) | — | |
| SCHEMBL65785 | 0.67 | — | — | |
| SCHEMBL193243 | 0.65 | — | — | |
| SCHEMBL1461465 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969923-A | Heteroaryl amino compounds, methods of preparation and use thereof | 北京鞍石生物科技有限责任公司 | 2023-10-31 | — | — | CN | claimed |
| US-9834548-B2 | Pyridazine compounds as JAK inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2017-12-05 | — | — | US | claimed |
| US-20170174673-A1 | PYRIDAZINE COMPOUNDS AS JAK INHIBITORS | ALEXION PHARMACEUTICALS, INC. | 2017-06-22 | — | — | US | claimed |
| WO-2015123453-A1 | PYRIDAZINE COMPOUNDS AS JAK INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2015-08-20 | — | — | WO | claimed |
| EP-1492536-B1 | 4-(N-PHENYLAMINO)-QUINAZOLINES / QUINOLINES AS TYROSINE KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-05-09 | — | — | EP | claimed |
| EP-2298305-A1 | 4-(N-Phenylamino)-quinazolines/quinolines as inhibitors of tyrosine kinases | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2011-03-23 | — | — | EP | claimed |
| JP-4537315-B2 | — | — | 2010-09-01 | — | — | JP | claimed |
| US-7666863-B2 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED (US) | 2010-02-23 | — | — | US | claimed |
| US-7456189-B2 | Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-25 | — | — | US | claimed |
| US-20070231318-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | SAHA ASHIS K | 2007-10-04 | — | — | US | claimed |
| EP-0216165-B1 | BENZODIPYRROLES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-11-23 | — | — | EP | claimed |
| EP-0318902-A2 | Use of linear annelated tricyclics as inhibitors of erythrocyte aggregation | Roche Diagnostics GmbH (DE) | 1989-06-07 | — | — | EP | claimed |
| US-4831032-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ISOTROPIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-16 | — | — | US | claimed |
| EP-0275888-A2 | Tricyclic benzimidazoles, process for their preparation and use as medicaments | Roche Diagnostics GmbH (DE) | 1988-07-27 | — | — | EP | claimed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | claimed |
| EP-0216165-A1 | Benzodipyrroles, processes for their preparation and pharmaceutical compositions containing these compounds | Roche Diagnostics GmbH (DE) | 1987-04-01 | — | — | EP | claimed |
| EP-0207483-A2 | Benzimidazoles, process for their preparation, medicaments containing them and intermediates | Roche Diagnostics GmbH (DE) | 1987-01-07 | — | — | EP | claimed |
| EP-0186010-A1 | Pyrrolo benzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1986-07-02 | — | — | EP | claimed |
| US-4582837-A | Imidazo[4,5-b] and [4,5-c]pyridine derivatives having cardiotonic activity | DR. KARL THOMAE GMBH (DE) | 1986-04-15 | — | — | US | claimed |
| EP-0098448-A2 | Imidazole derivatives, their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1984-01-18 | — | — | EP | claimed |