SCHEMBL9898539

SCHEMBL9898539

CO[SiH](OCCN(C)C)OCCN(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRM3 P20309 1/20 0.34
CHRNA4 P43681 1/20 0.34
CA12 O43570 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA1 P00915 1/20 0.33
HTR7 P34969 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898057 0.95 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL9897265 0.86 CHRM2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL22228733 0.78 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL9896847 0.77 KDM4E (0.33) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL9897972 0.77 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL9897750 0.77 KDM4E (0.33) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL557676 0.72 DNM1 (0.39) CA12CA2CA9ALDH1A1TSHR
SCHEMBL9898190 0.72 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRNB2
SCHEMBL9898571 0.72
SCHEMBL9899185 0.70 KMT2A (0.39) ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471798-B1 PROCESS FOR PRODUCTION OF SILANE COUPLING AGENTS BRIDGESTONE CORP (JP) 2015-08-19 EP claimed
EP-2471798-A1 PROCESS FOR PRODUCTION OF SILANE COUPLING AGENTS Bridgestone Corporation (JP) 2012-07-04 EP claimed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
US-9150595-B2 Process for producing silane coupling agent BRIDGESTONE CORPORATION (JP) 2015-10-06 US disclosed
EP-2471798-B1 PROCESS FOR PRODUCTION OF SILANE COUPLING AGENTS BRIDGESTONE CORP (JP) 2015-08-19 EP disclosed
EP-2471798-A1 PROCESS FOR PRODUCTION OF SILANE COUPLING AGENTS Bridgestone Corporation (JP) 2012-07-04 EP disclosed
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149929-A1 PROCESS FOR PRODUCING SILANE COUPLING AGENT HAO2, SAMM50, SKP2 CHRM2 4017/4885CHRM4 4026/4885CHRM5 4187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.