SCHEMBL9898980

SCHEMBL9898980

O=C(CCC(=NO[Si](c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.47
CTNNB1 P35222 3/20 0.45
WNT3A P56704 3/20 0.45
ALDH1A1 P00352 3/20 0.44
CYP2C19 P33261 2/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
LMNA P02545 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
MAPK1 P28482 2/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PPARA Q07869 2/20 0.41
HDAC1 Q13547 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898979 1.00 NR4A2 (0.47) NR4A2CTNNB1WNT3AALDH1A1CYP2C19
SCHEMBL9898975 0.91 L3MBTL1 (0.49) NR4A2CTNNB1WNT3AALDH1A1CYP2C19
SCHEMBL9898977 0.91 L3MBTL1 (0.49) NR4A2CTNNB1WNT3AALDH1A1CYP2C19
SCHEMBL2050834 0.91 PPARA (0.40) GAAMAPTL3MBTL1LMNAMAPK1
SCHEMBL2050836 0.91 PPARA (0.40) GAAMAPTL3MBTL1LMNAMAPK1
SCHEMBL9899246 0.86 NR4A2 (0.49) NR4A2CTNNB1WNT3AALDH1A1CYP2C19
SCHEMBL9899218 0.86 NR4A2 (0.49) NR4A2CTNNB1WNT3AALDH1A1CYP2C19
SCHEMBL2046809 0.84 PPARA (0.38) GAAMAPTL3MBTL1LMNAMAPK1
SCHEMBL2046807 0.84 PPARA (0.38) GAAMAPTL3MBTL1LMNAMAPK1
SCHEMBL9899313 0.84 NR4A2 (0.46) NR4A2CTNNB1WNT3AALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed