SCHEMBL9899167

SCHEMBL9899167

CON=C1C(=O)C(Cl)=C(Cl)C(Cl)=C1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.41
BCHE P06276 2/20 0.41
ACHE P22303 2/20 0.41
CES1 P23141 2/20 0.41
NSD2 O96028 1/20 0.41
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898918 0.76 CES2 (0.36) CES2BCHEACHECES1NSD2
SCHEMBL9898260 0.64 IDO1 (0.35) NSD2HSP90AA1TLR9DEPTOR
SCHEMBL15439389 0.62 DEPTOR (0.39) CES2BCHEACHECES1NSD2
SCHEMBL79009 0.62 CES2 (1.00) CES2BCHEACHECES1NSD2
SCHEMBL21327556 0.62 CES2 (0.90) CES2BCHEACHECES1NSD2
Chloranil SCHEMBL24049 0.58 CES2 (1.00) CES2BCHEACHECES1NSD2
Chloranil SCHEMBL4682884 0.58 CES2 (1.00) CES2BCHEACHECES1NSD2
SCHEMBL18536621 0.57 MEN1 (0.30) MEN1KMT2A
SCHEMBL1717135 0.57 MAPT (0.50) CES2BCHEACHECES1NSD2
SCHEMBL18536620 0.56 ALDH1A1 (0.43) MAPTMAPK1ALDH1A1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed