SCHEMBL9899203

SCHEMBL9899203

CC(=O)CC(CC(C)=NO[Si](c1ccccc1)(c1ccccc1)c1ccccc1)=NO[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
ALDH1A1 P00352 3/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
RECQL P46063 2/20 0.31
KDM4E B2RXH2 2/20 0.31
RAB9A P51151 2/20 0.30
CASP3 P42574 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
MAOB P27338 1/20 0.30
HPGD P15428 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899202 1.00 MAPT (0.33) MAPTSMN1; SMN2ALDH1A1L3MBTL1RECQL
SCHEMBL9898520 0.91 MAPT (0.36) MAPTALDH1A1L3MBTL1RECQLKDM4E
SCHEMBL9898522 0.91 MAPT (0.36) MAPTALDH1A1L3MBTL1RECQLKDM4E
SCHEMBL2044130 0.88 MAOB (0.33) MAPTSMN1; SMN2L3MBTL1MAOB
SCHEMBL2044132 0.88 MAOB (0.33) MAPTSMN1; SMN2L3MBTL1MAOB
SCHEMBL9898465 0.87 MAPT (0.34) MAPTALDH1A1L3MBTL1RECQLKDM4E
SCHEMBL9898468 0.87 MAPT (0.34) MAPTALDH1A1L3MBTL1RECQLKDM4E
SCHEMBL2050541 0.84 LMNA (0.36) MAPTL3MBTL1RECQLKDM4EMAOB
SCHEMBL2050543 0.84 LMNA (0.36) MAPTL3MBTL1RECQLKDM4EMAOB
SCHEMBL2044910 0.82 ALDH1A1 (0.36) MAPTSMN1; SMN2ALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed