Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119600 | 0.96 | KDM1A (0.33) | OPRL1OPRK1OPRM1KDM1ACSF1R | |
| SCHEMBL9940060 | 0.80 | PTGES (0.44) | — | |
| SCHEMBL9899766 | 0.78 | PTGES (0.35) | OPRL1OPRK1OPRM1KDM1A | |
| SCHEMBL9899436 | 0.78 | OPRL1 (0.39) | OPRL1 | |
| SCHEMBL9899450 | 0.76 | MAP2K7 (0.41) | KCNH2CSF1R | |
| SCHEMBL9939817 | 0.76 | KCNH2 (0.43) | OPRL1KDM1AKCNH2 | |
| SCHEMBL9940004 | 0.75 | PTGES (0.46) | — | |
| SCHEMBL9939955 | 0.74 | PTGES (0.33) | OPRK1KDM1A | |
| SCHEMBL9900234 | 0.74 | OPRK1 (0.37) | OPRL1OPRK1OPRM1KCNH2 | |
| SCHEMBL9940009 | 0.71 | OPRK1 (0.37) | OPRK1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649052-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |