Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939955 | 0.97 | PTGES (0.33) | PTGESCAMK2DOPRK1PRCPKDM1A | |
| SCHEMBL9899657 | 0.84 | PTGES (0.41) | PTGESOPRL1OPRM1OPRK1 | |
| SCHEMBL9900234 | 0.83 | OPRK1 (0.37) | PTGESCAMK2DOPRL1OPRM1OPRK1 | |
| SCHEMBL9939951 | 0.83 | PTGES (0.46) | PTGES | |
| SCHEMBL9939952 | 0.81 | PTGES (0.40) | PTGESOPRL1 | |
| SCHEMBL9940009 | 0.80 | OPRK1 (0.37) | CAMK2DOPRK1PRCPKDM1A | |
| SCHEMBL9899388 | 0.78 | OPRL1 (0.33) | OPRL1OPRM1OPRK1KDM1A | |
| SCHEMBL14119600 | 0.74 | KDM1A (0.33) | OPRL1OPRM1OPRK1KDM1A | |
| SCHEMBL9939926 | 0.72 | PTGES (0.49) | PTGES | |
| SCHEMBL9939817 | 0.72 | KCNH2 (0.43) | OPRL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649052-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |