Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900135 | 0.82 | BCL6 (0.39) | BCHEACHECHRNA7SMN1; SMN2TRPV1 | |
| SCHEMBL9899749 | 0.75 | SLC22A12 (0.42) | BCHEACHECHRNA7TRPV1MEN1 | |
| SCHEMBL9899393 | 0.75 | LPAR1 (0.40) | BCHEACHEP2RX7 | |
| SCHEMBL9899560 | 0.72 | LPAR1 (0.51) | BCHEACHE | |
| SCHEMBL1128597 | 0.71 | BCHE (0.49) | BCHEACHESMN1; SMN2TRPV1MEN1 | |
| SCHEMBL27741038 | 0.68 | ALDH1A1 (0.48) | SMN1; SMN2TRPV1MEN1PKMCASP3 | |
| SCHEMBL20940182 | 0.68 | TAAR1 (0.44) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL27449727 | 0.68 | TAAR1 (0.47) | SMN1; SMN2CYP1A2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL2339641 | 0.67 | LPAR1 (0.46) | SMN1; SMN2P2RX7MEN1PKMCASP3 | |
| SCHEMBL1247206 | 0.67 | SCN9A (0.61) | SMN1; SMN2TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648714-A2 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND USES THEREOF | Amira Pharmaceuticals, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078593-A2 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND USES THEREOF | AMIRA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | WO | disclosed |