SCHEMBL27449727

SCHEMBL27449727

O=C(O)OCCc1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.47
HIF1A Q16665 1/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
NR4A2 P43354 2/20 0.45
CTBP2 P56545 1/20 0.45
PLAAT3 P53816 2/20 0.44
PLAAT5 Q96KN8 2/20 0.44
PLAAT2 Q9NWW9 2/20 0.44
PLAAT4 Q9UL19 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CXCL8 P10145 1/20 0.44
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR3A P46098 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499879 0.84 MAOA (0.46) TAAR1HIF1ANPC1RAB9AHTR3E
SCHEMBL1821613 0.84 TAAR1 (0.50) TAAR1HIF1ANPC1RAB9ASMN1; SMN2
SCHEMBL20940182 0.82 TAAR1 (0.44) TAAR1HIF1ANPC1RAB9AL3MBTL1
SCHEMBL7096241 0.82 ESR2 (0.46) HIF1ANPC1SMN1; SMN2
SCHEMBL4374949 0.81 L3MBTL1 (0.59) NPC1RAB9AL3MBTL1NR4A2CTBP2
SCHEMBL27857019 0.81 TAAR1 (0.43) TAAR1HIF1ANPC1RAB9AL3MBTL1
SCHEMBL27332749 0.81 TAAR1 (0.52) TAAR1HIF1ANPC1RAB9AL3MBTL1
SCHEMBL145662 0.80 THRB (0.55) TAAR1HIF1ANPC1RAB9ACXCL8
SCHEMBL29716499 0.80 THRB (0.55) TAAR1HIF1ANPC1RAB9ACXCL8
SCHEMBL3891807 0.79 KMT2A (0.47) TAAR1HIF1ANPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1304458-C Process for preparing polycarbonate and apparatus for preparing polycarbonate GEN ELECTRIC (US) 2007-03-14 CN disclosed
CN-1555392-A Method for preparing polycarbonate and apparatus for preparing polycarbonate ͨ�õ�����˾ 2004-12-15 CN disclosed
CN-1131259-C Method for producing polycarbonate resin TEIJIN LTD (JP) 2003-12-17 CN disclosed
CN-1252817-A Process for producing polycarbonate resin TEIJIN LTD (JP) 2000-05-10 CN disclosed