SCHEMBL9899738

SCHEMBL9899738

O=C1Nc2ccccc2C1C1C(=O)Nc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.53
GSK3B P49841 2/20 0.47
BRPF1 P55201 1/20 0.47
CREBBP Q92793 1/20 0.47
TDO2 P48775 1/20 0.45
MAPT P10636 5/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
PARP1 P09874 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16566110 0.86 IDO1 (0.46) IDO1GSK3BBRPF1CREBBPTDO2
SCHEMBL11027115 0.84 CACNB4 (0.55) IDO1MAPT
SCHEMBL11029123 0.84 MAPT (0.45) IDO1GSK3BMAPT
SCHEMBL16566268 0.82 IDO1 (0.44) IDO1GSK3BBRPF1CREBBPTDO2
SCHEMBL7375443 0.81 MAPT (0.49) IDO1GSK3BBRPF1CREBBPTDO2
SCHEMBL18552441 0.81 MAPT (0.49) IDO1GSK3BBRPF1CREBBPTDO2
SCHEMBL824370 0.80 IDO1 (0.45) IDO1GSK3BBRPF1CREBBPTDO2
SCHEMBL23567209 0.80 BRPF1 (0.41) IDO1GSK3BBRPF1CREBBPMAPT
SCHEMBL9899341 0.80 IDO1 (0.45) IDO1GSK3BBRPF1CREBBPTDO2
SCHEMBL23785707 0.80 IDO1 (0.41) IDO1GSK3BBRPF1CREBBPTDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050122-A1 MOLECULAR DESIGN OF ELECTROACTIVE SPECIES AND MATERIALS PROCESSING METHODS IN ORGANIC REDOX FLOW BATTERIES BIOZEN BATTERIES, INC. (US) 2025-03-06 WO claimed
WO-2025050122-A1 MOLECULAR DESIGN OF ELECTROACTIVE SPECIES AND MATERIALS PROCESSING METHODS IN ORGANIC REDOX FLOW BATTERIES BIOZEN BATTERIES, INC. (US) 2025-03-06 WO disclosed
US-11007177-B2 Compositions comprising a combination of a substituted flavonoid and a substituted indole for treating ocular diseases UNIVERSITY OF MACAU (CN) 2021-05-18 US disclosed
WO-2012078519-A2 3-ACYLIDENE-2-OXOINDOLE DERIVATIVES FOR INHIBITION OF TRANSGLUTAMINASE 2 NUMERATE, INC. (US) 2012-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11007177-B2 Compositions comprising a combination of a substituted flavonoid and a substituted indole for treating ocular diseases IDO1, IDO2, SYVN1 IDO1 1/4885GSK3B 1508/4885BRPF1 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.