Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385907 | 0.73 | TAAR1 (0.36) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL21807606 | 0.72 | KDM4E (0.43) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL21807609 | 0.72 | KDM4E (0.43) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL3144077 | 0.71 | MAPT (0.52) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL7097279 | 0.70 | KDM4E (0.69) | KDM4EMAPTSMN1; SMN2ALDH1A1NPC1 | |
| Cgs-19281A SCHEMBL29769895 | 0.69 | KDM4E (0.58) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| Cgs-19281A SCHEMBL2930783 | 0.69 | KDM4E (0.58) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL31355003 | 0.68 | HTR6 (0.57) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL25897440 | 0.68 | HTR6 (0.57) | KDM4EMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL85996 | 0.68 | MAOB (0.62) | KDM4EMAPTSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078859-A2 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-06-14 | — | — | WO | disclosed |