Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906237 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2ADRA2CADRA2BADRA2A | |
| SCHEMBL15848618 | 0.73 | ALDH1A1 (0.39) | GABRA1GABRB2ADRA2CHTR1AALDH1A1 | |
| SCHEMBL15848437 | 0.73 | GABRA1 (0.47) | GABRA1GABRB2ADRA2CHTR1AALDH1A1 | |
| SCHEMBL3850180 | 0.73 | GABRA1 (0.42) | GABRA1GABRB2ADRA2CADRA2BADRA2A | |
| SCHEMBL29763626 | 0.71 | GABRA1 (0.56) | GABRA1GABRB2ADRA2CADRA2BADRA2A | |
| SCHEMBL173300 | 0.71 | GABRA1 (0.56) | GABRA1GABRB2ADRA2CADRA2BADRA2A | |
| Phosphine SCHEMBL28908229 | 0.69 | GABRA1 (0.54) | GABRA1GABRB2ADRA2CADRA2BADRA2A | |
| SCHEMBL10528834 | 0.69 | GABRA1 (0.54) | GABRA1GABRB2ADRA2CADRA2BADRA2A | |
| SCHEMBL19437729 | 0.69 | GABRA1 (0.54) | GABRA1GABRB2ADRA2CADRA2BADRA2A | |
| SCHEMBL11765775 | 0.69 | GABRA1 (0.54) | GABRA1GABRB2ADRA2CADRA2BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649131-A1 | SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | Dow Corning Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-2649113-A1 | SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | Dow Corning Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-2649114-A1 | SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS | Dow Corning Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| US-20130256741-A1 | Siloxane Compositions Suitable For Forming Encapsulants | DOW CORNING CORPORATION | 2013-10-03 | — | — | US | disclosed |
| US-20130256742-A1 | Siloxane-Compositions Including Metal-Oxide Nanoparticles Suitable For Forming Encapsulants | DOW CORNING CORPORATION (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2012078582-A1 | SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | DOW CORNING CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012078594-A1 | SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS | DOW CORNING CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012078617-A1 | SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | DOW CORNING CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |