Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900992 | 0.66 | RPS6KB2 (0.46) | — | |
| SCHEMBL9901079 | 0.65 | GLP1R (0.36) | GLP1R | |
| SCHEMBL9925837 | 0.65 | — | — | |
| SCHEMBL2210464 | 0.61 | GAA (0.33) | — | |
| SCHEMBL9901190 | 0.58 | ALDH1A1 (0.40) | GLP1R | |
| SCHEMBL14985414 | 0.57 | MAPT (0.34) | — | |
| SCHEMBL31073516 | 0.57 | ALDH1A1 (0.43) | — | |
| SCHEMBL9904722 | 0.56 | KDM4E (0.35) | — | |
| SCHEMBL8023256 | 0.56 | ADORA2A (0.55) | — | |
| SCHEMBL9904572 | 0.56 | KMT2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076966-A1 | SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS | LUPIN LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012076966-A1 | SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS | LUPIN LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |