Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899768 | 0.87 | RPS6KA3 (0.56) | RPS6KA3SLC22A12ALDH1A1ALOX15TSHR | |
| SCHEMBL5106705 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL1043517 | 0.72 | KDM4C (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11258140 | 0.72 | RPS6KA3 (0.68) | RPS6KA3SLC22A12 | |
| SCHEMBL30494180 | 0.72 | RPS6KA3 (0.68) | RPS6KA3SLC22A12 | |
| SCHEMBL15017796 | 0.70 | RAB9A (0.45) | — | |
| SCHEMBL6774875 | 0.70 | KDM4C (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4831443 | 0.70 | BCHE (0.46) | HSD17B10MEN1KMT2A | |
| SCHEMBL1503786 | 0.70 | KDM4C (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28824138 | 0.70 | KDM4E (0.53) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648714-A2 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND USES THEREOF | Amira Pharmaceuticals, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078593-A2 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND USES THEREOF | AMIRA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | WO | disclosed |