Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2752328 | 0.82 | SOS1 (0.53) | SOS1FFAR4KMT2ALMNAGFER | |
| SCHEMBL257919 | 0.82 | TEAD4 (0.48) | SOS1KMT2ALMNAGFERL3MBTL1 | |
| SCHEMBL920684 | 0.82 | KMT2A (0.50) | KMT2ALMNAGFERL3MBTL1SMN1; SMN2 | |
| SCHEMBL15075246 | 0.81 | LTA4H (0.48) | L3MBTL1MRGPRX4SMN1; SMN2ALDH1A1 | |
| SCHEMBL28061160 | 0.81 | LTA4H (0.48) | SOS1FFAR4KMT2ALMNAL3MBTL1 | |
| SCHEMBL257852 | 0.80 | SOS1 (0.50) | SOS1FFAR4KMT2ALMNAGFER | |
| SCHEMBL16616691 | 0.80 | MRGPRX4 (0.35) | SOS1FFAR4KMT2AGFERMRGPRX4 | |
| SCHEMBL12260917 | 0.79 | SOS1 (0.39) | SOS1FFAR4KMT2ALMNAGFER | |
| SCHEMBL3236124 | 0.79 | RAB9A (0.41) | KMT2ALMNAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL3235096 | 0.78 | HTR2A (0.47) | SOS1KMT2ALMNAGFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649050-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012075917-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |