Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988347 | 0.96 | MAPT (0.87) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL20293445 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL40510 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL257132 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2985078 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1050169 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12680242 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2803510 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL740489 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2802414 | 0.89 | HSD17B10 (1.00) | MAPTHSD17B10CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110020837-A1 | Method for isolating or identifying a target protein interacting with a lipid in a cell | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110020837-A1 | Method for isolating or identifying a target protein interacting with a lipid in a cell | PLIN5, PLIN1, PLIN3 | MAPT 4763/4885HSD17B10 442/4885CYP1A2 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.