SCHEMBL740489

SCHEMBL740489

C#CCCCCCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2D6 P10635 1/20 1.00
MAPT P10636 1/20 1.00
CYP2C9 P11712 1/20 1.00
CYP2C19 P33261 1/20 1.00
TSHR P16473 4/20 0.60
LMNA P02545 2/20 0.60
NFKB1 P19838 1/20 0.60
PMP22 Q01453 1/20 0.60
PTPN7 P35236 3/20 0.54
HMGCR P04035 3/20 0.54
GPR84 Q9NQS5 3/20 0.50
FFAR1 O14842 1/20 0.50
FFAR4 Q5NUL3 1/20 0.50
PPARG P37231 3/20 0.48
PPARD Q03181 3/20 0.48
PPARA Q07869 3/20 0.48
HDAC11 Q96DB2 2/20 0.48
TDP1 Q9NUW8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL979048 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL1050169 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL40510 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL2802414 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL20293445 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL2803510 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL2985078 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL12680242 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL257132 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL29377936 1.00 HSD17B10 (1.00) HSD17B10CYP1A2CYP2D6MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136965-A Isolated polypeptide of targeted MPP8 protein and application thereof 苏州系统医学研究所 2025-06-13 CN claimed
CN-116444258-B Foamed ceramic prepared from steel slag and red mud and process thereof 江门市俞嘉科技有限公司 2024-08-20 CN claimed
CN-101863732-B Synthesis method of end-group alkyne SHANGHAI RUIYI MEDICAL TECHNOLOGY CO LTD 2013-08-07 CN claimed
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS INC (US) 2026-03-12 US disclosed
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
EP-4665332-A2 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF Differentiated Therapeutics Inc (US) 2025-12-24 EP disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
EP-4634184-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING KINASES VIA UBIQUITIN PROTEOSOME PATHWAY Crossfire Oncology Holding B.V. (NL) 2025-10-22 EP disclosed
US-20250288573-A1 DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2025-09-18 US disclosed
EP-3893934-B1 INSULIN CONJUGATES SANOFI SA (FR) 2025-09-10 EP disclosed
US-20250206798-A1 INSULIN CONJUGATES SANOFI SA (FR) 2025-06-26 US disclosed
US-20060111359-A1 enzyme inhibitor for treating sleep disorders THE SCRIPPS RESEARCH INSTITUTE (US) 2006-05-25 US disclosed
US-20060111269-A1 Depot preparations SYMRISE AG (DE) 2006-05-25 US disclosed
CN-1703407-A fatty acid amide hydrolase inhibitors SCRIPPS RESEARCH INST (US) 2005-11-30 CN disclosed
EP-1549624-A2 INHIBITORS OF FATTY ACID AMIDE HYDROLASE The Scripps Research Institute (US) 2005-07-06 EP disclosed
WO-2004033652-A2 INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2004-04-22 WO disclosed
US-20030114352-A1 Depot preparations SYMRISE GMBH & CO. KG (DE) 2003-06-19 US disclosed
US-20030083376-A1 Depot preparations SYMRISE GMBH & CO. KG (DE) 2003-05-01 US disclosed
US-4871868-A FROM AN ORGANIC HALIDE OR AN ARYL SULFONATE AND AN ALKALI METAL ACETYLIDE, 1,3-DIALKYL-2-IMIDAZOLIDINONE PROMOTER TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-03 US disclosed
EP-0284237-A1 Production of substituted acetylenic compounds Takeda Chemical Industries, Ltd. (JP) 1988-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111359-A1 enzyme inhibitor for treating sleep disorders FAAH, FAAH2, HCRTR2 HSD17B10 118/4885CYP1A2 46/4885CYP2D6 285/4885
US-20030083376-A1 Depot preparations FABP4, ADH1C, LIPE HSD17B10 45/4885CYP1A2 198/4885CYP2D6 666/4885
US-20250288573-A1 DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS CRBN, CD4, CDR2 HSD17B10 3514/4885CYP1A2 4199/4885CYP2D6 3818/4885
US-20030114352-A1 Depot preparations FABP4, LIPE, GPR119 HSD17B10 44/4885CYP1A2 155/4885CYP2D6 580/4885
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL HSD17B10 1083/4885CYP1A2 1719/4885CYP2D6 2393/4885
US-20250206798-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R HSD17B10 1314/4885CYP1A2 1696/4885CYP2D6 1147/4885
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF CDK2, CCNK, CCNC HSD17B10 1607/4885CYP1A2 1915/4885CYP2D6 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.