Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | RORA | P35398 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | RORB | Q92753 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901566 | 0.93 | HTR6 (0.46) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14107129 | 0.70 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9905344 | 0.70 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9976723 | 0.70 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL551644 | 0.70 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL644925 | 0.70 | CYP1A2 (0.49) | HTR6 | |
| SCHEMBL24438167 | 0.70 | HTR6 (0.60) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29114461 | 0.70 | HTR6 (0.60) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL554428 | 0.68 | CNR2 (0.63) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3475552 | 0.68 | HTT (0.50) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130320269-A1 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | THE UNIVERSITY OF MANCHESTER (GB) | 2013-12-05 | — | — | US | disclosed |
| EP-2649073-A2 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | The University Of Manchester (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076886-A2 | NOVEL PROCESS AND COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-06-14 | — | — | WO | disclosed |