⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9793362 | 0.65 | — | — | |
| Water SCHEMBL11126730 | 0.65 | — | — | |
| SCHEMBL8595406 | 0.63 | — | — | |
| SCHEMBL1231204 | 0.63 | — | — | |
| SCHEMBL8529606 | 0.61 | — | — | |
| SCHEMBL186948 | 0.61 | — | — | |
| SCHEMBL20038146 | 0.60 | — | — | |
| SCHEMBL40163 | 0.60 | — | — | |
| SCHEMBL12720522 | 0.59 | — | — | |
| SCHEMBL324235 | 0.59 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665472-B1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SOLVOTRIN INNOVATIONS LTD (IE) | 2022-07-06 | — | — | EP | disclosed |
| US-9566342-B2 | Compounds for treatment of heart failure | SOLVOTRIN INNOVATIONS LIMITED (IE) | 2017-02-14 | — | — | US | disclosed |
| US-20130338118-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SOLVOTRIN INNOVATIONS LIMITED (IE) | 2013-12-19 | — | — | US | disclosed |
| EP-2665472-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | Solvotrin Innovations Limited (IE) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012076667-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SOLVOTRIN INNOVATIONS LIMITED (IE) | 2012-06-14 | — | — | WO | disclosed |