SCHEMBL9901343

SCHEMBL9901343

CC(C)(O)c1coc(Cn2ncc([N+](=O)[O-])n2)n1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 17/20 0.50
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1704162 0.88 FPR2 (0.46) FPR2ALDH1A1
SCHEMBL9900612 0.86 FPR2 (0.38) FPR2
SCHEMBL1703915 0.80 FPR2 (0.50) FPR2
SCHEMBL9901605 0.79 FPR2 (0.49) FPR2
SCHEMBL27930825 0.78 FPR2 (0.40) FPR2ALDH1A1
SCHEMBL27832762 0.77 FPR2 (0.36) FPR2
SCHEMBL9900144 0.76 FPR2 (0.46) FPR2ALDH1A1
SCHEMBL9900171 0.74 FPR2 (0.37) FPR2ALDH1A1
SCHEMBL2328492 0.74 FPR2 (0.33) FPR2
SCHEMBL9901446 0.74 FPR2 (0.36) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2648724-B1 HYDROXYLATED AMINOTRIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2016-09-21 EP disclosed
US-9346793-B2 Hydroxylated aminotriazole derivatives as ALX receptor agonists ACTELION PHARMACEUTICALS, LTD. (CH) 2016-05-24 US disclosed
US-9346793-B2 Hydroxylated aminotriazole derivatives as ALX receptor agonists ACTELION PHARMACEUTICALS, LTD. (CH) 2016-05-24 US disclosed
US-9346793-B2 Hydroxylated aminotriazole derivatives as ALX receptor agonists ACTELION PHARMACEUTICALS, LTD. (CH) 2016-05-24 US disclosed
EP-2648724-A1 HYDROXYLATED AMINOTRIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS Actelion Pharmaceuticals Ltd. (CH) 2013-10-16 EP disclosed
US-20130267569-A1 Hydroxylated Aminotriazole Derivatives as ALX Receptor Agonists IDORSIA PHARMACEUTICALS LTD (CH) 2013-10-10 US disclosed
US-20130267569-A1 Hydroxylated Aminotriazole Derivatives as ALX Receptor Agonists IDORSIA PHARMACEUTICALS LTD (CH) 2013-10-10 US disclosed
US-20130267569-A1 Hydroxylated Aminotriazole Derivatives as ALX Receptor Agonists IDORSIA PHARMACEUTICALS LTD (CH) 2013-10-10 US disclosed
CN-103249413-A Hydroxylated aminotriazole derivatives as ALX receptor agonists ACTELION PHARMACEUTICALS LTD 2013-08-14 CN disclosed
WO-2012077051-A1 HYDROXYLATED AMINOTRIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2012-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267569-A1 Hydroxylated Aminotriazole Derivatives as ALX Receptor Agonists ADORA1, ADORA3, HCAR3 FPR2 333/4885ALDH1A1 505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.