Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.35 |
| ▸ | FPR3 | P25089 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901606 | 1.00 | FPR2 (0.35) | FPR2FPR3RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9902154 | 0.92 | KDM4E (0.38) | FPR2FPR3RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9901873 | 0.89 | USP30 (0.36) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16994489 | 0.89 | P2RX7 (0.38) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16994497 | 0.89 | P2RX7 (0.37) | RAB9ASMN1; SMN2MEN1KMT2AEPHX1 | |
| SCHEMBL9902381 | 0.89 | P2RX7 (0.37) | RAB9ASMN1; SMN2MEN1KMT2AEPHX1 | |
| SCHEMBL9902380 | 0.89 | P2RX7 (0.37) | RAB9ASMN1; SMN2MEN1KMT2AEPHX1 | |
| SCHEMBL9902049 | 0.88 | EGFR (0.33) | MEN1KMT2ALMNAKDM4EGAA | |
| SCHEMBL9902048 | 0.88 | EGFR (0.33) | MEN1KMT2ALMNAKDM4EGAA | |
| SCHEMBL17271384 | 0.87 | KDM4E (0.44) | KMT2ALMNAEPHX1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |