Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902217 | 0.92 | KDM4E (0.38) | USP30THRBALDH1A1KMT2ACYP2C19 | |
| SCHEMBL9902214 | 0.92 | KDM4E (0.38) | USP30THRBALDH1A1KMT2ACYP2C19 | |
| SCHEMBL16994489 | 0.89 | P2RX7 (0.38) | ALDH1A1KMT2ACYP2C19KDM4EGAA | |
| SCHEMBL9901609 | 0.89 | FPR2 (0.35) | KMT2AKDM4EGAASMN1; SMN2LMNA | |
| SCHEMBL9901606 | 0.89 | FPR2 (0.35) | KMT2AKDM4EGAASMN1; SMN2LMNA | |
| SCHEMBL9902380 | 0.89 | P2RX7 (0.37) | THRBALDH1A1KMT2ACYP2C19KDM4E | |
| SCHEMBL9902381 | 0.89 | P2RX7 (0.37) | THRBALDH1A1KMT2ACYP2C19KDM4E | |
| SCHEMBL16994497 | 0.89 | P2RX7 (0.37) | THRBALDH1A1KMT2ACYP2C19KDM4E | |
| SCHEMBL9902494 | 0.88 | MEN1 (0.37) | USP30ALDH1A1KMT2ACYP2C19CYP2C9 | |
| SCHEMBL9902498 | 0.88 | MEN1 (0.37) | USP30ALDH1A1KMT2ACYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |