Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 4/20 | 0.39 |
| ▸ | UNG | P13051 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9927517 | 0.84 | HTR2A (0.46) | HSD11B1PLK1UNGHTR2ASOAT1 | |
| SCHEMBL9901011 | 0.83 | UNG (0.40) | HSD11B1PLK1UNGHTR2APLK3 | |
| SCHEMBL24175223 | 0.80 | HSD11B1 (0.47) | HSD11B1PLK1SOAT1 | |
| SCHEMBL9901473 | 0.78 | GPR3 (0.40) | HSD11B1PLK1UNGHTR2APLK3 | |
| SCHEMBL5371426 | 0.75 | HSD11B1 (0.48) | HSD11B1HTR2ACTSVCTSLMAPK8 | |
| SCHEMBL16678699 | 0.73 | HSD11B1 (0.63) | HSD11B1HTR2ACTSVCTSLRARB | |
| SCHEMBL23432180 | 0.73 | PSMB5 (0.51) | HSD11B1MAPKAPK2UNG | |
| SCHEMBL13251178 | 0.73 | RARB (0.45) | HSD11B1UNGCTSVCTSLGPR3 | |
| SCHEMBL3728181 | 0.72 | CTSV (0.49) | HSD11B1HTR2ACTSVCTSLRARB | |
| SCHEMBL10491901 | 0.72 | HSD11B1 (0.55) | HSD11B1HTR2ACTSVCTSLRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130320269-A1 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | THE UNIVERSITY OF MANCHESTER (GB) | 2013-12-05 | — | — | US | disclosed |
| EP-2649073-A2 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | The University Of Manchester (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076886-A2 | NOVEL PROCESS AND COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-06-14 | — | — | WO | disclosed |