Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903750 | 0.91 | TSHR (0.45) | THRBOPRM1OPRD1OPRK1CHRM5 | |
| SCHEMBL27927061 | 0.89 | TSHR (0.52) | THRBOPRM1OPRD1OPRK1CHRM5 | |
| SCHEMBL9075028 | 0.84 | SLC1A3 (0.44) | THRBTDP1HTTPOLBAPEX1 | |
| SCHEMBL723115 | 0.83 | OPRM1 (0.47) | OPRM1OPRD1OPRK1CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL27528734 | 0.82 | OPRM1 (0.46) | OPRM1OPRD1OPRK1CHRM5CHRM1 | |
| SCHEMBL11921516 | 0.81 | THRB (0.55) | THRBTDP1HTTPOLBAPEX1 | |
| SCHEMBL28273043 | 0.80 | HTT (0.49) | THRBTDP1HTTPOLBAPEX1 | |
| SCHEMBL22566492 | 0.80 | THRB (0.53) | THRBTDP1HTTPOLBAPEX1 | |
| SCHEMBL8336532 | 0.79 | CHRM5 (0.42) | OPRM1OPRD1OPRK1CHRM5CHRM1 | |
| SCHEMBL20809649 | 0.78 | OPRM1 (0.48) | OPRM1OPRD1OPRK1CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076288-A1 | COMPOSITE COMPRISING NANOPARTICLES AND METHOD OF MAKING NANOPARTICLES | UNIVERSITE DE LIEGE (BE) | 2012-06-14 | — | — | WO | disclosed |
| EP-2462898-A1 | Composite comprising nanoparticles and method for making nanoparticles | Université de Liège (BE) | 2012-06-13 | — | — | EP | disclosed |