SCHEMBL990337

SCHEMBL990337

COc1cccc(-c2ccc(N)c(OC)c2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.71
ALDH1A1 P00352 3/20 0.71
TSHR P16473 1/20 0.71
HSD17B10 Q99714 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
MAOB P27338 2/20 0.53
FYN P06241 2/20 0.52
HDAC2 Q92769 1/20 0.51
MAP4K4 O95819 1/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2E1 P05181 1/20 0.50
CYP2C8 P10632 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2A6 P11509 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP4B1 P13584 1/20 0.50
CYP2B6 P20813 1/20 0.50
CYP3A5 P20815 1/20 0.50
CYP2A7 P20853 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30482672 1.00 CYP3A4 (0.71) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL29655214 0.85 MAOB (0.56) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL29399235 0.84 ALDH1A1 (1.00) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL48945 0.84 ALDH1A1 (1.00) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL3732151 0.84 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL3784708 0.84 ALDH1A1 (0.74) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL358211 0.83 ALDH1A1 (0.80) CYP3A4ALDH1A1TSHRHSD17B10TDP1
SCHEMBL22651658 0.83 CA12 (0.59) CYP3A4TSHRMAOBFYNCYP1A1
SCHEMBL30196125 0.83 CA12 (0.59) CYP3A4TSHRMAOBFYNCYP1A1
Hydrochloric Acid SCHEMBL622811 0.82 ALDH1A1 (0.95) CYP3A4ALDH1A1TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170277080-A1 ENDLESS BELT FOR IMAGE FORMING APPARATUS, BELT UNIT FOR IMAGE FORMING APPARATUS, IMAGE FORMING APPARATUS, RESIN COMPOSITION, MANUFACTURING METHOD OF ENDLESS BELT FOR IMAGE FORMING APPARATUS, AND MANUFACTURING METHOD OF RESIN COMPOSITION FUJI XEROX CO., LTD. (JP) 2017-09-28 US disclosed
US-20130224653-A1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND METHOD FOR PRODUCING THE SAME PI R&D CO., LTD (JP) 2013-08-29 US disclosed
US-20110136061-A1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND PROCESS FOR PRODUCING THE SAME ITATANI HIROSHI 2011-06-09 US disclosed
EP-1614704-B1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND METHOD FOR PRODUCING THE SAME PI R & D CO LTD (JP) 2011-01-19 EP disclosed
US-20070106056-A1 Crosslinked polyimide, composition comprising the same and method for producing the same PI R&D CO., LTD. (JP) 2007-05-10 US disclosed
EP-1614704-A1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND METHOD FOR PRODUCING THE SAME PI R & D Co. Ltd (JP) 2006-01-11 EP disclosed
US-20030035031-A1 Ink jet head and production method of the same ITO TAKESHI (JP) 2003-02-20 US disclosed
EP-0604319-B1 Polyimide solution compositions and process for preparing same ITATANI HIROSHI (JP) 1999-04-28 EP disclosed
US-5502143-A BLOCK POLYMERS PI MATERIAL RESEARCH LABORATORY (JP) 1996-03-26 US disclosed