SCHEMBL358211

SCHEMBL358211

COc1cc(-c2ccccc2)ccc1N

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.80
HSD17B10 Q99714 3/20 0.80
TDP1 Q9NUW8 2/20 0.80
CYP3A4 P08684 2/20 0.80
TSHR P16473 1/20 0.80
ADRA2B P18089 1/20 0.54
PTGS1 P23219 1/20 0.54
MAPT P10636 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
HPGD P15428 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
APP P05067 1/20 0.49
CASP1 P29466 1/20 0.47
IDO1 P14902 1/20 0.47
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL6573242 0.90 ALDH1A1 (0.91) ALDH1A1HSD17B10TDP1CYP3A4TSHR
SCHEMBL48945 0.89 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CYP3A4TSHR
SCHEMBL29399235 0.89 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CYP3A4TSHR
Hydrochloric Acid SCHEMBL30913021 0.87 ALDH1A1 (0.95) ALDH1A1HSD17B10TDP1CYP3A4TSHR
Hydrochloric Acid SCHEMBL29494721 0.87 ALDH1A1 (0.95) ALDH1A1HSD17B10TDP1CYP3A4TSHR
Hydrochloric Acid SCHEMBL622811 0.87 ALDH1A1 (0.95) ALDH1A1HSD17B10TDP1CYP3A4TSHR
Ammonia Solution, Strong SCHEMBL2259240 0.87 ALDH1A1 (0.95) ALDH1A1HSD17B10TDP1CYP3A4TSHR
Methane SCHEMBL28975440 0.87 ALDH1A1 (0.95) ALDH1A1HSD17B10TDP1CYP3A4TSHR
Hydrochloric Acid SCHEMBL30053031 0.87 ALDH1A1 (0.95) ALDH1A1HSD17B10TDP1CYP3A4TSHR
Hydrochloric Acid SCHEMBL3947578 0.87 ALDH1A1 (0.95) ALDH1A1HSD17B10TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100475-A1 COMPOSITION FOR IMAGE RECORDING AND METHOD FOR PRODUCING SAME キヤノン株式会社 2025-05-15 WO disclosed
CN-116478070-A Compound, pharmaceutical composition and application thereof in field of vasodilation or antiviral 山东第一医科大学(山东省医学科学院) 2023-07-25 CN disclosed
CN-115093359-B Compound, pharmaceutical composition and application thereof in field of vasodilation or antiviral 山东第一医科大学(山东省医学科学院) 2023-06-09 CN disclosed
CN-115093359-A Compound, pharmaceutical composition and application of compound and pharmaceutical composition in field of blood vessel expansion or virus resistance 山东第一医科大学(山东省医学科学院) 2022-09-23 CN disclosed
US-11434245-B2 WNT pathway modulators AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-09-06 US disclosed
US-11434245-B2 WNT pathway modulators AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-09-06 US disclosed
CN-114846080-A Thermoplastic molding compositions containing polyalkylene terephthalates 巴斯夫欧洲公司 2022-08-02 CN disclosed
CN-108467370-B Triazole naphthoquinone bi-aromatic ring derivative or triazole naphthoquinone bi-aromatic heterocyclic derivative, and preparation method and application thereof 四川大学 2021-11-23 CN disclosed
CN-108137806-B Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2021-05-28 CN disclosed
CN-111205459-B Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2021-05-28 CN disclosed
US-5438123-A Miticides, nematocides UNIROYAL CHEMICAL COMPANY, INC. (US) 1995-08-01 US disclosed
EP-0477819-B1 Benzimidazole derivatives, their preparation and use NEUROSEARCH AS (DK) 1995-03-15 EP disclosed
EP-0641316-A1 INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES. UNIROYAL CHEM CO INC (US) 1995-03-08 EP disclosed
US-5367093-A Pesticides UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-11-22 US disclosed
EP-0343574-B1 4(1H)-quinolone derivatives KIRIN BREWERY (JP) 1994-07-27 EP disclosed
WO-1993010083-A1 INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-05-27 WO disclosed
US-5200422-A Benzimidazole derivatives, their preparation and use NEUROSEARCH A/S (DK) 1993-04-06 US disclosed
EP-0477819-A2 Benzimidazole derivatives, their preparation and use NEUROSEARCH A/S (DK) 1992-04-01 EP disclosed
US-5081121-A Cardiotonic agents KIRIN BEER KABUSHIKI KAISHA (JP) 1992-01-14 US disclosed
EP-0343574-A1 4(1H)-quinolone derivatives KIRIN BEER KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11434245-B2 WNT pathway modulators WNT1, WNT3A, WNT3 ALDH1A1 2377/4885HSD17B10 1022/4885TDP1 3949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.