Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980277 | 0.87 | NTRK1 (0.58) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| SCHEMBL29399235 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| SCHEMBL48945 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| SCHEMBL3783522 | 0.85 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| SCHEMBL358211 | 0.85 | ALDH1A1 (0.80) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| Ammonia Solution, Strong SCHEMBL2259240 | 0.84 | ALDH1A1 (0.95) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| Methane SCHEMBL28975440 | 0.84 | ALDH1A1 (0.95) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| Hydrochloric Acid SCHEMBL29494721 | 0.84 | ALDH1A1 (0.95) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| Hydrochloric Acid SCHEMBL622811 | 0.84 | ALDH1A1 (0.95) | ALDH1A1CYP3A4HSD17B10TDP1TSHR | |
| Hydrochloric Acid SCHEMBL30913021 | 0.84 | ALDH1A1 (0.95) | ALDH1A1CYP3A4HSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885CYP3A4 177/4885HSD17B10 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.