Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 15/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902843 | 0.81 | AAK1 (0.50) | MTORPIK3CA | |
| SCHEMBL9902619 | 0.80 | GRM5 (0.51) | — | |
| SCHEMBL9902856 | 0.79 | GRM5 (0.47) | — | |
| SCHEMBL9903795 | 0.79 | NR4A2 (0.42) | — | |
| SCHEMBL9903615 | 0.79 | EGLN1 (0.39) | — | |
| SCHEMBL9905385 | 0.79 | NOS3 (0.43) | MTORPIK3CA | |
| SCHEMBL9902735 | 0.79 | PIK3CA (0.42) | MTORPIK3CA | |
| SCHEMBL9903770 | 0.78 | MTOR (0.40) | MTORPIK3CA | |
| SCHEMBL6157594 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL9903071 | 0.76 | NTRK3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178742-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-07-12 | — | — | US | disclosed |
| EP-2462142-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-06-13 | — | — | EP | disclosed |
| CN-102471334-A | Metabotropic glutamate receptor modulators | MERZ PHARMA GMBH & CO KGAA | 2012-05-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178742-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | GRM5, GRIK5, GRM1 | MTOR 2226/4885PIK3CA 2885/4885ADK 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.