Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9905724 | 0.92 | CA12 (0.50) | CA12CA2CA3CA4CA6 | |
| SCHEMBL12794518 | 0.92 | CA12 (0.57) | CA12CA2CA3CA4CA6 | |
| SCHEMBL82581 | 0.92 | CA12 (0.57) | CA12CA2CA3CA4CA6 | |
| SCHEMBL15444951 | 0.92 | CA12 (0.57) | CA12CA2CA3CA4CA6 | |
| SCHEMBL30952353 | 0.88 | CA12 (0.53) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL5055542 | 0.85 | CA12 (0.50) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL5055557 | 0.85 | CA12 (0.50) | CA12CA2CA3CA4CA6 | |
| SCHEMBL14212668 | 0.81 | ALDH1A1 (0.47) | CA12CA2CA3CA4CA6 | |
| SCHEMBL5055552 | 0.81 | CA12 (0.47) | CA12CA2CA3CA4CA6 | |
| SCHEMBL14495473 | 0.81 | CA12 (0.79) | CA12CA2CA3CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793581-B1 | NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING | DU PONT (US) | 2016-03-02 | — | — | EP | disclosed |
| US-20160050926-A1 | NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING | E I DU PONT DE NEMOURS AND COMPANY | 2016-02-25 | — | — | US | disclosed |
| US-9204644-B2 | Nanoparticles compositions containing polymers and anthranilic acid diamide insecticides for propagule coating | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150296781-A1 | ACRYLATE/METHACRYLATE-BASED TRIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING | E. I. DUPONT DE NEMOURS AND COMPANY | 2015-10-22 | — | — | US | disclosed |
| US-9149039-B2 | Anthranilic diamide/polymer propagule-coating compositions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-06 | — | — | US | disclosed |
| US-20140357482-A1 | ANTHRANILIC DIAMIDE/POLYMER PROPAGULE-COATING COMPOSITIONS | CORTEVA AGRISCIENCE LLC | 2014-12-04 | — | — | US | disclosed |
| US-20140357483-A1 | NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING | CORTEVA AGRISCIENCE LLC | 2014-12-04 | — | — | US | disclosed |
| EP-2793582-A1 | ANTHRANILIC DIAMIDE/POLYMER PROPAGULE-COATING COMPOSITIONS | E. I. Du Pont de Nemours and Company (US) | 2014-10-29 | — | — | EP | disclosed |
| EP-2793581-A1 | NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING | E. I. Du Pont de Nemours and Company (US) | 2014-10-29 | — | — | EP | disclosed |
| WO-2014168601-A1 | ACRYLATE/METHACRYLATE-BASED TRIBLOCK COPOLYMER / ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-10-16 | — | — | WO | disclosed |
| US-8575065-B2 | Acrylate/methacrylate-based star copolymer/anthranilic diamide compositions for propagle coating | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-05 | — | — | US | disclosed |
| US-8569268-B2 | Acrylate/methacrylate-based diblock copolymer/anthranilic diamide compositions for propagule coating | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-29 | — | — | US | disclosed |
| US-8563469-B2 | Acrylate/methacrylate-based random copolymer/anthranilic diamide compositions for propagule coating | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-22 | — | — | US | disclosed |
| WO-2013096497-A1 | NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013096479-A1 | ANTHRANILIC DIAMIDE/POLYMER PROPAGULE-COATING COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-27 | — | — | WO | disclosed |
| US-20120149567-A1 | ACRYLATE/METHACRYLATE-BASED STAR COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGLE COATING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149563-A1 | ACRYLATE/METHACRYLATE-BASED RANDOM COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149566-A1 | ACRYLATE/METHACRYLATE-BASED DIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150296781-A1 | ACRYLATE/METHACRYLATE-BASED TRIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING | DDT, MTDH, API5 | CA12 2989/4885CA2 2084/4885CA3 1476/4885 |
| US-20120149566-A1 | ACRYLATE/METHACRYLATE-BASED DIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING | DDT, APMAP, MTDH | CA12 2805/4885CA2 1900/4885CA3 1480/4885 |
| US-20160050926-A1 | NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING | DDT, MTDH, AGPS | CA12 1261/4885CA2 422/4885CA3 211/4885 |
| US-20120149563-A1 | ACRYLATE/METHACRYLATE-BASED RANDOM COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING | AGPS, THEM6, DDT | CA12 3434/4885CA2 2258/4885CA3 1830/4885 |
| US-20140357482-A1 | ANTHRANILIC DIAMIDE/POLYMER PROPAGULE-COATING COMPOSITIONS | DDT, AGPS, ANTXR2 | CA12 1420/4885CA2 734/4885CA3 511/4885 |
| US-20120149567-A1 | ACRYLATE/METHACRYLATE-BASED STAR COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGLE COATING | STAMBP, MTDH, AGPS | CA12 3576/4885CA2 2308/4885CA3 1310/4885 |
| US-20140357483-A1 | NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING | MTDH, DDT, AGPS | CA12 682/4885CA2 244/4885CA3 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.