Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | MMP2 | P08253 | 2/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | COMT | P21964 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | METAP2 | P50579 | 1/20 | 0.68 |
| ▸ | METAP1 | P53582 | 1/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL30108907 | 1.00 | TSHR (0.68) | TSHRMMP2CHRM1COMTADRA1A | |
| Phenanthroline SCHEMBL25421956 | 0.84 | LMNA (0.61) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL29365411 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL29716519 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL253313 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL37189 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL22553419 | 0.80 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL22466317 | 0.80 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL21195162 | 0.80 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL22467701 | 0.80 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772439-B | A kind of quinoline benzimidazole Group IVB list half metallocene and its preparation method and application and the method for olefinic polyreaction | 中国石油化工股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-103772439-A | Quinoline-benzimidazole IVB group mono-Cp complex, preparation method and application thereof and method for polymerization reaction of olefin | CHINA PETROLEUM & CHEMICAL | 2014-05-07 | — | — | CN | disclosed |
| EP-2648703-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TRANS-CINNAMALDEHYDE AND ITS USE IN THE TREATMENT OF INFECTIONS | Septeos (FR) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076717-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TRANS-CINNAMALDEHYDE AND ITS USE IN THE TREATMENT OF INFECTIONS | SOCIETE DE DEVELOPPEMENT SCIENTIFIQUE - SDS (FR) | 2012-06-14 | — | — | WO | disclosed |