SCHEMBL9905977

SCHEMBL9905977

COc1cc(OC)cc(C(=O)Oc2ccc(C#N)cc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.56
MAPT P10636 4/20 0.52
F2 P00734 1/20 0.49
LMNA P02545 2/20 0.49
CYP1A2 P05177 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
POLB P06746 1/20 0.48
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
TP53 P04637 3/20 0.47
ALDH1A1 P00352 2/20 0.46
CYP2D6 P10635 1/20 0.45
HIF1A Q16665 1/20 0.45
PARP15 Q460N3 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP2 Q9UGN5 1/20 0.45
MGLL Q99685 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074037 0.89 CYP1A2 (0.58) THRBMAPTF2LMNACYP1A2
SCHEMBL12362581 0.89 CYP1A2 (0.58) THRBMAPTF2LMNACYP1A2
SCHEMBL8074450 0.89 CYP1A2 (0.58) THRBMAPTF2LMNACYP1A2
SCHEMBL11115730 0.86 ESR1 (0.62) THRBMAPTF2SMN1; SMN2POLB
SCHEMBL9906018 0.85 MEN1 (0.58) THRBMAPTLMNASMN1; SMN2CYP2C9
SCHEMBL5881227 0.84 THRB (0.61) THRBMAPTF2LMNACYP1A2
SCHEMBL12736320 0.84 THRB (0.61) THRBMAPTF2LMNACYP1A2
SCHEMBL9906015 0.83 THRB (0.53) THRBMAPTF2LMNASMN1; SMN2
SCHEMBL10016814 0.83 ESR1 (0.58) THRBMAPTLMNACYP1A2SMN1; SMN2
SCHEMBL12619291 0.83 ESR1 (0.58) THRBMAPTSMN1; SMN2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8425991-B2 Cellulose acylate film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8425991-B2 Cellulose acylate film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 US disclosed
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8097188-B2 Method of manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2012-01-17 US disclosed
US-8097188-B2 Method of manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2012-01-17 US disclosed
US-20110128478-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF MANUFACTURING PROTECTIVE FILM FOR POLARIZING PLATE KONICA MINOLTA OPTO, INC. (JP) 2011-06-02 US disclosed
US-7951434-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-05-31 US disclosed
US-20070258141-A1 Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070258141-A1 Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070231505-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070231505-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070046864-A1 Optical resin film and polarizing film and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD., (JP) 2007-03-01 US disclosed
US-20070046864-A1 Optical resin film and polarizing film and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD., (JP) 2007-03-01 US disclosed