SCHEMBL9906015

SCHEMBL9906015

COc1cc(OC)c(C(=O)Oc2ccc(C#N)cc2)c(OC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.53
MAPT P10636 3/20 0.49
KMT2A Q03164 2/20 0.49
F2 P00734 1/20 0.46
POLB P06746 1/20 0.45
TP53 P04637 3/20 0.44
CYP3A4 P08684 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
USP2 O75604 1/20 0.43
MAPK1 P28482 1/20 0.43
LMNA P02545 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
ALOX15 P16050 1/20 0.42
CNR1 P21554 1/20 0.42
CASP1 P29466 1/20 0.42
CNR2 P34972 1/20 0.42
CASP7 P55210 1/20 0.42
MGLL Q99685 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9905848 0.87 F2 (0.50) THRBMAPTF2POLBTP53
SCHEMBL9905853 0.86 THRB (0.46) THRBMAPTF2POLBTP53
SCHEMBL9905851 0.84 KMT2A (0.66) THRBMAPTKMT2ASMN1; SMN2LMNA
SCHEMBL9905977 0.83 THRB (0.56) THRBMAPTKMT2AF2POLB
SCHEMBL13186069 0.83 KMT2A (0.55) KMT2ACYP3A4SMN1; SMN2USP2MAPK1
SCHEMBL9905852 0.81 THRB (0.52) THRBMAPTKMT2AF2POLB
SCHEMBL29226757 0.80 KMT2A (0.51) MAPTKMT2APOLBTP53CYP3A4
SCHEMBL9906019 0.79 ALDH1A1 (0.54) THRBMAPTKMT2AF2POLB
SCHEMBL13963805 0.79 KMT2A (0.62) MAPTKMT2APOLBCYP3A4SMN1; SMN2
SCHEMBL8074037 0.78 CYP1A2 (0.58) THRBMAPTKMT2AF2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8425991-B2 Cellulose acylate film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8425991-B2 Cellulose acylate film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 US disclosed
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8097188-B2 Method of manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2012-01-17 US disclosed
US-8097188-B2 Method of manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2012-01-17 US disclosed
US-20110128478-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF MANUFACTURING PROTECTIVE FILM FOR POLARIZING PLATE KONICA MINOLTA OPTO, INC. (JP) 2011-06-02 US disclosed
US-7951434-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-05-31 US disclosed
US-7951434-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-05-31 US disclosed
US-20070258141-A1 Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070231505-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070231505-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
WO-2007029843-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2007-03-15 WO disclosed
US-20070046864-A1 Optical resin film and polarizing film and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD., (JP) 2007-03-01 US disclosed
US-20070046864-A1 Optical resin film and polarizing film and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD., (JP) 2007-03-01 US disclosed