SCHEMBL8074450

SCHEMBL8074450

COc1ccc(C(=O)Oc2ccc(C#N)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.58
LMNA P02545 2/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
THRB P10828 1/20 0.58
MAPT P10636 4/20 0.55
KMT2A Q03164 4/20 0.55
PRSS1 P07477 2/20 0.55
ACR P10323 2/20 0.55
GFER P55789 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
ALDH1A1 P00352 3/20 0.52
CYP2D6 P10635 1/20 0.52
HIF1A Q16665 1/20 0.52
PARP15 Q460N3 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
F2 P00734 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074037 1.00 CYP1A2 (0.58) CYP1A2LMNACYP2C9CYP2C19SMN1; SMN2
SCHEMBL12362581 1.00 CYP1A2 (0.58) CYP1A2LMNACYP2C9CYP2C19SMN1; SMN2
SCHEMBL5881227 0.95 THRB (0.61) CYP1A2LMNACYP2C9CYP2C19SMN1; SMN2
SCHEMBL12736320 0.95 THRB (0.61) CYP1A2LMNACYP2C9CYP2C19SMN1; SMN2
SCHEMBL29038955 0.91 ALDH1A1 (0.58) CYP1A2MAPTPRSS1ACRCA1
SCHEMBL8496209 0.91 ALDH1A1 (0.58) CYP1A2MAPTPRSS1ACRCA1
SCHEMBL10017357 0.90 ESR1 (0.58) CYP1A2LMNACYP2C9CYP2C19SMN1; SMN2
SCHEMBL10016814 0.90 ESR1 (0.58) CYP1A2LMNACYP2C9CYP2C19SMN1; SMN2
SCHEMBL9285422 0.89 RAB9A (0.64) SMN1; SMN2THRBMAPTKMT2AALDH1A1
SCHEMBL9905977 0.89 THRB (0.56) CYP1A2LMNACYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11021272-A None JP disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 US disclosed
US-20230018608-A1 HORIZONTALLY ORIENTED LIQUID CRYSTAL CURED FILM AND LAMINATE INCLUDING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-01-19 US disclosed
US-20210403811-A1 PERPENDICULARLY ALIGNED LIQUID CRYSTAL CURED FILM AND LAMINATE INCLUDING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-30 US disclosed
US-11186669-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2021-11-30 US disclosed
US-20210189239-A1 LIQUID CRYSTAL COMPOSITION, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2021-06-24 US disclosed
EP-3345939-B1 POWDER MIXTURE DAINIPPON INK & CHEMICALS (JP) 2020-10-14 EP disclosed
WO-2020022246-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL LIGHT CONTROL ELEMENT JNC株式会社 2020-01-30 WO disclosed
US-10479844-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2019-11-19 US disclosed
EP-3246340-B1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DAINIPPON INK & CHEMICALS (JP) 2019-10-09 EP disclosed
US-20070190268-A1 Optical film and optical compensatory film, polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-08-16 US disclosed
US-20070081115-A1 Polarizing plate and image display device using the same FUJIFILM CORPORATION (JP) 2007-04-12 US disclosed
US-20070046864-A1 Optical resin film and polarizing film and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD., (JP) 2007-03-01 US disclosed
US-20070046864-A1 Optical resin film and polarizing film and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD., (JP) 2007-03-01 US disclosed
CN-1678948-A Switchable electro-optical laminates AVERY DENNISON CORP (US) 2005-10-05 CN disclosed
US-6013748-A RADIATION TRANSPARENT OPTICAL FILM JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2000-01-11 US disclosed
JP-H1121272-A AROMATIC OLIGOESTER, ITS PRODUCTION AND USE AGENCY OF IND SCIENCE & TECHNOL 1999-01-26 JP disclosed
CN-1034195-C Liquid crystal color display and method MANCHESTER R & D PARTNERSHIP (US) 1997-03-05 CN disclosed
CN-86101192-A LIQUID CRYSTAL COLOR DISPLAY AND METHOD 1986-09-24 CN disclosed
US-4444844-A LEUCO DYE, SPECIFIC PHENYL BENZOATES AS DEVELOPER AND PROMOTER, FOR HIGH SPEED AND DENSITY RICOH CO., LTD. (JP) 1984-04-24 US disclosed